Gene information
Official symbol GSTT1
Official full name glutathione S-transferase theta 1
Gene type protein-coding gene
Chromosome22q11.23
Gene familySoluble glutathione S-transferases
Resources
Entrez Gene 2952
HGNC HGNC:4641
Ensembl ENSG00000277656
Vega OTTHUMG00000190354
UCSC uc002zze.4
GO terms: 14 records
GO Description Category LogP Number of genes Detail
GO:0004601 peroxidase activity GO Molecular Functions -5.52369866 7 More
GO:0006518 peptide metabolic process GO Biological Processes -2.74792434 15 More
GO:0006575 cellular modified amino acid metabolic process GO Biological Processes -7.43961662 26 More
GO:0006749 glutathione metabolic process GO Biological Processes -3.95134537 6 More
GO:0006790 sulfur compound metabolic process GO Biological Processes -3.12963557 12 More
GO:0009636 response to toxic substance GO Biological Processes -18.1818984 46 More
GO:0016209 antioxidant activity GO Molecular Functions -11.3593886 22 More
GO:0016491 oxidoreductase activity GO Molecular Functions -14.1519969 39 More
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor GO Molecular Functions -5.30702712 7 More
GO:0043603 cellular amide metabolic process GO Biological Processes -1.84597279 17 More
GO:0097237 cellular response to toxic substance GO Biological Processes -13.7473733 28 More
GO:0098754 detoxification GO Biological Processes -12.4136065 17 More
GO:0098869 cellular oxidant detoxification GO Biological Processes -12.6410846 24 More
GO:1990748 cellular detoxification GO Biological Processes -12.8821364 16 More
KEGG pathways: 6 records
KEGG Description Category LogP Number of genes Detail
hsa00983 Drug metabolism - other enzymes KEGG Pathway -2.57730801 5 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05204 Chemical carcinogenesis - DNA adducts KEGG Pathway -6.89688307 9 More
hsa05207 Chemical carcinogenesis - receptor activation KEGG Pathway -7.05448873 28 More
hsa05208 Chemical carcinogenesis - reactive oxygen species KEGG Pathway -3.44838603 10 More
hsa05225 Hepatocellular carcinoma KEGG Pathway -5.07719186 21 More
Drug-Gene interaction
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Related drugs: 10 records
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
GSTT1 null genotype genomics acute myocardial infarction[diagnosis] acute myocardial infarction Cornelis MC et al. Am J Clin Nutr. 2007
GSTT1 null genotype genomics acute myocardial infarction[diagnosis] acute myocardial infarction Singh N et al. Cardiology. 2011
GSTT1 null genotype genomics myocardial infarction[diagnosis] myocardial infarction Cora T et al. Mol Biol Rep. 2013
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